Poor-quality sleep during the third trimester of pregnancy can increase the odds of weight gain and metabolic abnormalities in offspring once they reach adulthood, according to a new study published online in the journal Diabetes.

The researchers linked the excess weight and changes in metabolism to epigenetic modifications that reduce expression of the gene for adiponectin—a hormone that helps regulate several metabolic processes, including glucose regulation. Lower levels of adiponectin correlate with increased body fat and reduced activity.