For patients with acute eosinophilic pneumonia (AEP), comorbid traction bronchiectasis (TBE) may be tied to poor prognosis and mortality, according to a study in Respiratory Investigation.
Researchers looked at clinical data from 41 patients (median age 66) diagnosed with AEP.
Four of the 41 patients with AEP analyzed died after not responding to corticosteroid treatment (mean survival after diagnosis 17 days). While three of the fatal AEP cases were idiopathic, one was medication-related. Patients with fatal AEP had a median eosinophil percentage of 59%, based on BAL.
All four people who died had been diagnosed with TBE, according to HRCT results. Because no TBE had been confirmed before AEP diagnosis, researchers suggested that the condition was secondary to AEP.