Researchers from Nationwide Children’s Hospital investigated if genetics play a role in childhood asthma control and prevention.
Data were compared between patients with or without family history of asthma (parents, siblings). Mean, standard deviation, median, and interquartile range (depending on the normality of the data) measured the distribution scores.
Change in asthma indicators over 3-6-month increments were evaluated by Poisson Mixed Effects Model. The alpha level of significance was less than or equal to .05.
The collected data included information from 395 children aged 2 to 17 years, [median 6 (3, 9)]; 61% was male. The duration of symptoms in years at diagnosis was 3 (1, 6), and the median age in years was 1.5 (1, 3). In 285 (72%) of children, a family history of asthma was reported.
Over time, a family history of asthma did not prove to be a significant covariate in asthma improvement.