Genetic Differences in Influenza and COVID-19 Response
New research found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry.
Tag: genetics
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The Future of CRISPR for Cystic Fibrosis Just Got a Boost
The National Institutes of Health is funding a grant of more than $2 million to adapt tools that may increase the accuracy of CRISPR gene editing for cystic fibrosis.
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Novel Cystic Fibrosis Drug KB407 Granted Orphan Drug Designation
Krystal Biotech Inc's KB407 is an inhaled, repeat-dose gene therapy for cystic fibrosis currently in the preclinical phase.
Novel Stem Cell Therapy for COVID-19-related ARDS in Development
A novel stem cell therapy using generation mesenchymal stem cells (MSCs) is in development for acute respiratory distress syndrome in COVID-19 patients.
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Stem Cells in COPD Lungs Drive Mucins, Fibrosis, Inflammation
Researchers say three pathogenic stem cell variants in COPD patients’ lungs drive mucin overproduction, tissue fibrosis, and inflammation.
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Scientists Uncover Gene mutation that drives lung cancer in Asian Populations
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered that a genetic variant in a gene called MET is responsible for more aggressive growth of head and neck, and lung cancers. The study was published in the scientific journal Nature Communications.
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AI Software Scans Blood for Lung Cancer DNA Mutations
Researchers created an artificial intelligence program that can evaluate patients for lung cancer. The program works by analyzing the blood for DNA mutations, The Guardian reports.
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Removing Body Clock Gene Protects Mice Against Pneumonia
Removing the clock gene BMAL1 makes bacteria-engulfing defense cells in the body more effective, new research found.
Read MoreNew Drug Target Discovered for the Lung Disease PAH
Scientists have identified a molecular pathway that contributes to the development of pulmonary arterial hypertension (PAH), a severe, often fatal condition that has no cure. The discovery, published Sept. 12, 2019,...
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New Clues About Genetic Susceptibility, Diversity of COPD
A population-based study expands the number of genetic variants associated with the risk of developing COPD, providing new insights into the disease.
Read MoreIncreased Lung Cancer Risk for Smokers with Gene Mutation
Smokers with a BRCA2 gene mutation had a 25% chance of developing lung cancer in their lifetime, according to researchers from The Institute of Cancer Research in the UK. It is common knowledge that smoking is the leading risk...
Read MoreGenomic Epidemiology Advances Investigations Of Disease Outbreaks
A new field called genomic epidemiology is using next-generation DNA sequencing to better inform public health officials faced with ongoing outbreaks.
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Deadly Immune ‘Storm’ Caused by Emergent Flu Infections
Researchers have identified key elements of a severe immune overreaction (cytokine ‘storm’) that can sicken and kill patients infected with certain strains of flu virus.
Read MoreImmune Response Predicts Severity of Influenza
Patients with elevated levels of three particular immune system regulators, or cytokines, early in influenza diagnosis were more likely to develop severe symptoms and be hospitalized.
Read MoreHuman Genome Editing Could Help Eliminate Diseases Like CF
Scientists at the Gladstone Institutes have discovered a way to efficiently edit human DNA, one letter at a time, which could one day help eliminate diseases like cystic fibrosis.
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