Two opposing expert commentaries on e-cigarette use published in BMC Medicine call for a rational discussion based on evidence.
Much of the current research in this area can suffer from methodological limitations, significant conflicts of interest and inconsistent results. To address these issues so that evidence-based decisions can be made, BMC Medicine has launched an article collection on the topic. The commentaries by Peter Hajek and Charlotta Pisinger are the first in a series of debates in this special article collection. Further critiques from invited experts will be published in due course on a spectrum of topics about e-cigarettes, from research agendas, health policies and regulation, to psychiatric and public health outcomes.