SARS-CoV-2 Antibody Test Helps Select Donor Blood Samples for Therapeutic Use
A new COVID-19 antibody assay was able to detect IgG and IgM antibodies to determine viable donor samples for therapeutic use and clinical trials.
Category: Clinical Trials
Clinical Trials
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Clinical Trials
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NIH Expanding Convalescent Plasma Clinical Trials
Two randomized, placebo-controlled clinical trials funded by the NIH are expanding enrollment to further evaluate convalescent plasma for COVID-19.
Clinical Trials
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First Chronic Bronchitis Patients Treated with RejuvenAir ‘Cryospray’
A clinical study will evaluate the safety and feasibility of treating chronic bronchitis patients with the RejuvenAir System, a "cryotherapy" spray that freezes and ablates unwanted tissue inside the lungs.
Cystic Fibrosis: Phase 1B Trial Begins for Arginase Inhibitor
Calithera Biosciences Inc has dosed the first patients in its Phase 1b clinical trial of the arginase inhibitor CB-280 in adult patients with cystic fibrosis and chronic airway infection.
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Novavax Begins Phase 1/2 Study of COVID-19 Vaccine Candidate
Novavax Inc has enrolled the first participants in a Phase 1/2 clinical trial of its coronavirus vaccine candidate, NVX‑CoV2373.
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Clinical Trials Testing Inhaled Nitric Oxide as COVID-19 Therapy
This clinical trial will monitor patients with mild to moderate cases of COVID-19 to see how they respond to inhaled nitric oxide as a treatment.
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Remdesivir Prevents COVID-19 Progression in Monkeys
Early treatment with the antiviral drug remdesivir significantly reduced clinical disease and damage to the lungs of rhesus macaques infected with SARS-CoV-2.
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Unclear Results for Gilead’s Remdesivir for Severe Covid-19
The first clinical results for remdesivir’s effectiveness on severe COVID-19 demonstrated clinical improvements but remain unclear because no control group was included in the study.
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Phase 3 Trial to Test Inhaled Nitric Oxide for Pulmonary Fibrosis-related Pulmonary Hypertension
Bellerophon Therapeutics will soon initiate a Phase 3 trial for its INOpulse inhaled nitric oxide therapy for the treatment of pulmonary hypertension associated with pulmonary fibrosis.
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Pulmonary Hypertension Treatment Trial Shows Positive Results
Acceleron Pharma’s investigational treatment for pulmonary arterial hypertension showed positive outcomes in a mid-stage trial, the company announced on Monday.
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Oxbryta FDA-approved for Sickle Cell Disease
Sickle cell disease patients receiving Oxbryta (1500mg) experienced a 51.1% increase in hemoglobin response rate compared to 6.5% in the placebo group.
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Clinical Trial on Universal Flu Vaccine Begins
An experimental universal flu vaccine is being administered to patients as part of a clinical drug trial at the National Institutes of Health, reports CNN.
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NanoFlu Flu Vaccine Begins Phase 3 Trial
Novavax has initiated a Phase 3 clinical trial for NanoFlu, its recombinant quadrivalent seasonal influenza vaccine candidate, in adults aged 65 and over.
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Mixed Results for Orkambi in Cystic Fibrosis Patients
Orkambi appeared to improve lung function and body weight and reduce the need for intravenous antibiotic treatment in adult and pediatric cystic fibrosis patients, but 18% of patients did not tolerate the therapy.
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Early Data Promising for Cryospray COPD Treatment
A 12-month feasibility study of the RejuvenAir Metered Cryospray system revealed “clinically meaningful improvements” in COPD patients with chronic bronchitis.
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