Clinical Trial of RSV Vaccine Underway
MV-012-968 is an intranasal live attenuated RSV vaccine candidate being developed as a needle-free, adjuvant-free vaccine to protect infants and at-risk, older adults.
Category: Clinical Trials
Clinical Trials
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Clinical Trials
Latest
Clinical Trial Begins for 2nd-Gen COVID-19 Vaccine
A Phase I/II clinical trial in the Netherlands will test AKS-452, a COVID-19 vaccine candidate that is shelf-stable for at least 4 months without refrigeration.
Clinical Trials
Latest
Monoclonal Antibodies Effective against MERS Coronavirus in First Human Trial
The first Phase 1 clinical trial of two monoclonal antibodies to treat Middle East respiratory syndrome coronavirus (MERS-CoV) found that they were well tolerated and generally safe when administered simultaneously to healthy adults.
aTyr Pharma Begins Phase 1b/2a Clinical Trial for Sarcoidosis Drug
aTyr Pharma Inc has completed the target enrollment in its Phase 1b/2a clinical trial for ATYR1923 in patients with pulmonary sarcoidosis.
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COVID-19 Trial to Compare Dexamethasone + Remdesivir versus Baricitinib + Remdesivir
The NIAID is enrolling participants in its ACTT-4 clinical trial to assess the effectiveness of dexamethasone plus remdesivir, compared to baricitinib plus remdesivir.
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NIH Expanding Convalescent Plasma Clinical Trials
Two randomized, placebo-controlled clinical trials funded by the NIH are expanding enrollment to further evaluate convalescent plasma for COVID-19.
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Positive Data for Merck’s Pneumococcal Conjugate Vaccine Candidate
Two Phase 3 studies of Merck’s investigational 15-valent pneumococcal conjugate vaccine met their primary immunogenicity objectives.
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AstraZeneca Halts Phase 3 Study of COVID-19 Vaccine after Illness
“A potentially unexplained illness” in a recipient of AstraZeneca’s COVID-19 vaccine candidate AZD1222 has halted the company’s phase 3 clinical trial, the AP reports.
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Positive Data for Inhaled Molgramostim for Autoimmune Pulmonary Alveolar Proteinosis (aPAP)
A phase 3 study of inhaled molgramostim therapy found the drug resulted in greater improvements in pulmonary gas transfer and functional health status than placebo in patients with Autoimmune Pulmonary Alveolar Proteinosis (aPAP).
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AstraZeneca’s COVID-19 Vaccine Candidate Begins Phase 3 Trial
The multi-site, Phase 3 clinical trial will enroll 30,000 adults in order to evaluate AstraZeneca’s investigational COVID-19 vaccine known as AZD1222.
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COVID-19: Clinical Trial Starts for Remdesivir plus Interferon β1a
The National Institutes of Health has initiated a randomized, controlled clinical trial evaluating the safety and efficacy of the antiviral remdesivir (Gilead Sciences) plus the immunomodulator interferon beta-1a (Merck) in patients with COVID-19.
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More Positive Results for Moderna’s COVID-19 Vaccine Candidate
Moderna’s mRNA-1273 induced neutralizing antibodies in mice when given as two intramuscular injections of a 1-microgram dose three weeks apart.
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Cystic Fibrosis: Phase 1B Trial Begins for Arginase Inhibitor
Calithera Biosciences Inc has dosed the first patients in its Phase 1b clinical trial of the arginase inhibitor CB-280 in adult patients with cystic fibrosis and chronic airway infection.
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Novavax Begins Phase 1/2 Study of COVID-19 Vaccine Candidate
Novavax Inc has enrolled the first participants in a Phase 1/2 clinical trial of its coronavirus vaccine candidate, NVX‑CoV2373.
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Remdesivir Improved Time to Recovery in COVID-19 Patients
Remdesivir was most beneficial for hospitalized COVID-19 patients with severe disease who required supplemental oxygen, according to an NEJM-published study.
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