NIH Expanding Convalescent Plasma Clinical Trials
Two randomized, placebo-controlled clinical trials funded by the NIH are expanding enrollment to further evaluate convalescent plasma for COVID-19.
Category: Clinical Trials
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Novavax Begins Phase 1/2 Study of COVID-19 Vaccine Candidate
Novavax Inc has enrolled the first participants in a Phase 1/2 clinical trial of its coronavirus vaccine candidate, NVX‑CoV2373.
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First Chronic Bronchitis Patients Treated with RejuvenAir ‘Cryospray’
A clinical study will evaluate the safety and feasibility of treating chronic bronchitis patients with the RejuvenAir System, a "cryotherapy" spray that freezes and ablates unwanted tissue inside the lungs.
Oxbryta FDA-approved for Sickle Cell Disease
Sickle cell disease patients receiving Oxbryta (1500mg) experienced a 51.1% increase in hemoglobin response rate compared to 6.5% in the placebo group.
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Clinical Trial on Universal Flu Vaccine Begins
An experimental universal flu vaccine is being administered to patients as part of a clinical drug trial at the National Institutes of Health, reports CNN.
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NanoFlu Flu Vaccine Begins Phase 3 Trial
Novavax has initiated a Phase 3 clinical trial for NanoFlu, its recombinant quadrivalent seasonal influenza vaccine candidate, in adults aged 65 and over.
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Mixed Results for Orkambi in Cystic Fibrosis Patients
Orkambi appeared to improve lung function and body weight and reduce the need for intravenous antibiotic treatment in adult and pediatric cystic fibrosis patients, but 18% of patients did not tolerate the therapy.
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Early Data Promising for Cryospray COPD Treatment
A 12-month feasibility study of the RejuvenAir Metered Cryospray system revealed “clinically meaningful improvements” in COPD patients with chronic bronchitis.
Read MoreBidding War Rages for Abandoned Tuberculosis Sanatorium
An unlikely bidding war has erupted over a former tuberculosis sanatorium in upstate New York that has been abandoned for nearly half a century, reports Fox News. In recent days, online haggling for Saratoga County Homestead in...
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Studies Could Accelerate Precision Medicine for Asthma
More complex studies that integrate multiple layers of asthma data have begun, but additional work is needed.
Read MoreAsthma Associated with Indoor Allergen Sensitization
Research from AAAAI 2019 found associations between asthma and patient sensitization to at least one of three allergens studied.
Read MoreBacteria in Preemies Ups Bronchopulmonary Dysplasia Risk
Babies born very prematurely are more likely to have Ureaplasma bacteria, which increases their mortality risk and likelihood of bronchopulmonary dysplasia.
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Zerbaxa Trial Hits Endpoints Treating HAP, VAP
Zerbaxa (ceftolozane and tazobactam) demonstrated non-inferiority to meropenem in 28-day all-cause mortality in the treatment of hospital-acquired pneumonia or ventilator-associated pneumonia.
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New Diagnostic Guideline for Idiopathic Pulmonary Fibrosis
The ATS, ERS, Japanese Respiratory Society and Latin American Thoracic Society have issued a new international guideline to help physicians diagnosis idiopathic pulmonary fibrosis (IPF).
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Phase 2 Trial to Investigate Role of NOX Enzymes in IPF
Do NOX enzymes play a pivotal role in idiopathic pulmonary fibrosis (IPF)? This is the question...
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