Lab-grown mini lungs have been successfully transplanted into immunosuppressed mice, where the structures were able to survive, grow and mature, according to University of Michigan researchers.
Scientists used numerous signaling pathways involved with cell growth and organ formation to coax stem cells — the body’s master cells — to make the miniature lungs.
The team used a biodegradable scaffold, which had been developed for transplanting tissue into animals, to achieve successful transplantation of the mini lungs into mice.
