Dysregulation of proteostasis is an emerging common pathomechanism for chronic lung diseases in the adult and aged patient, according to German researchers publishing in the journal Molecular and Cellular Pediatrics.
There is also rising evidence that sporadic impairment of protein homeostasis contributes to early disease onset in pediatric lung disorders beyond the well-known hereditary proteostasis disorders such as cystic fibrosis and AAT deficiency.
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