Children with cystic fibrosis differed from children without the disease in the quality and frequency of their breathing while asleep, according to a study recently published in Pediatrics.
Children with cystic fibrosis had lower oxyhemoglobin saturation (95% ± 1.6% vs. 98% ± 0.6%; P = .005) compared with healthy age and BMI-matched patients. Further, children with cystic fibrosis had a higher respiratory rate (19.5 ± 4.9 breaths per minute vs. 16.5 ± 1.2 breaths per minute; P = .03) during rapid-eye movement sleep, as well as a higher inspiratory flow limitation (44.1% ± 24.7% vs. 12.1% ± 13.5%; P = .007).
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