According to a study in the Annals of the American Thoracic Society, children with cystic fibrosis (CF) with acute lung function decline had a greater likelihood of recovery after receiving antibiotic therapy.

The researchers found that new antibiotic treatment was associated with an increased likelihood of recovery to 90 percent of baseline (P < 0.001), especially for hospitalization compared to no new antibiotic (odds ratio, 2.79).

All four outpatient treatments (home intravenous antibiotic, inhaled antibiotic, oral quinolone antibiotic, or other oral antibiotic) were associated with greater likelihood of recovery compared to no treatment (odds ratios, 1.27 to 1.64); however, inpatient treatment was better than outpatient treatments (odds ratio, 1.94).

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