Researchers have linked variations in the mix of microorganisms in cystic fibrosis patients’ airways to their disease outcomes.
Researchers decide to see if the prevalence and relative abundance of typical CF pathogens and anaerobic microorganisms play a role in the severity of patients’ disease and their lung function.
They analyzed 631 sputum samples collected over 10 years from 111 patients.
They discovered a link between variations in the prevalance of the six typical CF pathogens, plus nine anaerobic species, and changes in a patient’s disease stage and lung function.
