Polycystic ovary syndrome (PCOS) increased risk for spirometric restriction, according to research at ERS 2019.

  • Results showed PCOS was associated with a 10% higher risk for spirometric restriction without an indication of pleiotropy.
  • Similar results were seen using adjusted Mendelian randomization methods for pleiotropy and limiting analysis to women without asthma or SNPs in European women.
  • Estimates were also similar among women with normal weight and overweight.
  • No association was detected between obstructed airflow and PCOS.

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