Patients with uncontrolled asthma had a unique nasal bacteria composition that included elevated levels of Bacteroidetes, compared to nonasthmatics or asthmatics with controlled asthma, according to a study in the Journal of Allergy and Clinical Immunology.
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The study included 72 participants divided into groups: exacerbated asthma (20), nonexacerbated asthma (31) and nonasthmatics (21). Analysis showed that, at the phylum level, Bacteroidetes and Proteobacteria were significantly elevated in those with both nonexacerbated and exacerbated asthma.
Prevotella (Bacteroidetes), Alkanindiges (Proteobacteria), and Gardnerella (Actinobacteria), were elevated in those with uncontrolled asthma, while Dialister (Firmicutes) was higher in those with nonexacerbated asthma.