Children who develop asthma or allergies have an altered immune response to intestinal bacteria in the mucous membranes even when infants, according to a new study from Linköping University, Sweden, and Center for Advanced Research in Public Health, Spain.
The results also suggests that the mother’s immune defence plays a role in the development of asthma and allergies in children.
“Children who subsequently developed allergies had a lower fraction of IgA antibodies bound to their intestinal bacteria when aged 12 months than children who did not. This difference may suggest that the barrier function of the mucous membranes is less effective in children who later develop allergies. The lack of IgA was particularly noticeable in children who developed asthma during the first seven years of life,” researchers said.
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