Diluted Manuka honey can prevent early biofilm formation, according to a study published online Sept. 26 in the Journal of Clinical Pathology.

Researchers found that honey gave a dose-dependent reduction in biofilm formation in mixed cultures of Escherichia coli strain ATC 25922 and Proteus mirabilis, strain 7002. In addition, all cultures were inhibited maximally at 72 hours.

“Manuka honey at dilutions as low as 3.3 percent weight/volume in some protocols and at 10 percent or above in all protocols tested significantly inhibits bacterial attachment to a vinyl substrate and reduces further early biofilm development,” the authors write.

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